Browsing Brage INN by Author "Dusek, Petr"
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Cerebral Iron Deposition in Neurodegeneration
Dusek, Petr; Hofer, Tim; Alexander, Jan; Roos, Per M.; Aaseth, Jan Olav (Peer reviewed; Journal article, 2022)Disruption of cerebral iron regulation appears to have a role in aging and in the pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron accumulation include reactive oxygen species ... -
Iron chelation in the treatment of neurodegenerative diseases
Dusek, Petr; Schneider, Susanne A.; Aaseth, Jan (Journal article; Peer reviewed, 2016)Disturbance of cerebral iron regulation is almost universal in neurodegenerative disorders. There is a growing body of evidence that increased iron deposits may contribute to degenerative changes. Thus, the effect of iron ... -
Prevention of progression in Parkinson’s disease
Aaseth, Jan; Dusek, Petr; Roos, Per M. (Peer reviewed; Journal article, 2018)Environmental influences affecting genetically susceptible individuals seem to contribute significantly to the development of Parkinson’s disease (PD). Xenobiotic exposure including transitional metal deposition into ... -
Treatment strategies in Alzheimer’s disease: a review with focus on selenium supplementation
Aaseth, Jan; Alexander, Jan; Bjørklund, Geir; Hestad, Knut; Dusek, Petr; Roos, Per M.; Alehagen, Urban (Journal article; Peer reviewed, 2016)Alzheimer’s disease (AD) is a neurodegenerative disorder presenting one of the biggest healthcare challenges in developed countries. No effective treatment exists. In recent years the main focus of AD research has been on ...