Browsing Brage INN by Author "Ellegren, Hans"
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Genomic consequences of intensive inbreeding in an isolated wolf population
Kardos, Marty; Åkesson, Mikael; Fountain, Toby; Flagstad, Øystein; Liberg, Olof; Olason, Pall; Sand, Håkan; Wabakken, Petter; Wikenros, Camilla; Ellegren, Hans (Journal article, 2017)Inbreeding (mating between relatives) is a major concern for conservation as it decreases the fitness of offspring and can increase the extinction risk of populations. While pedigrees have traditionally been used to measure ... -
Whole-genome resequencing of temporally stratified samples reveals substantial loss of haplotype diversity in the highly inbred Scandinavian wolf population
Viluma, Agnese; Flagstad, Øystein; Åkesson, Mikael; Wikenros, Camilla; Sand, Håkan; Wabakken, Petter; Ellegren, Hans (Peer reviewed; Journal article, 2022)Genetic drift can dramatically change allele frequencies in small populations and lead to reduced levels of genetic diversity, including loss of segregating variants. However, there is a shortage of quantitative studies ...