• Hibernating brown bears are protected against atherogenic dyslipidemia 

      Giroud, Sylvain; Chery, Isabelle; Arrivé, Mathilde; Prost, Michel; Zumsteg, Julie; Heintz, Dimitri; Evans, Alina; Gauquelin-Koch, Guillemette; Arnemo, Jon Martin; Swenson, Jon E.; Lefai, Etienne; Bertile, Fabrice; Simon, Chantal; Blanc, Stéphane (Peer reviewed; Journal article, 2021)
      To investigate mechanisms by which hibernators avoid atherogenic hyperlipidemia during hibernation, we assessed lipoprotein and cholesterol metabolisms of free-ranging Scandinavian brown bears (Ursus arctos). In winter- ...
    • Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears 

      Ebert, Thomas; Painer, Johanna; Bergman, Peter; Qureshi, Abdul Rashid; Giroud, Sylvain; Stalder, Gabrielle; Kublickiene, Karolina; Göritz, Frank; Vetter, Sebastian G.; Bieber, Claudia; Fröbert, Ole; Arnemo, Jon Martin; Zedrosser, Andreas; Redtenbacher, Irene; Shiels, Paul; Johnson, Richard J.; Stenvinkel, Peter (Peer reviewed; Journal article, 2020)
      Experimental studies suggest involvement of trimethylamine N-oxide (TMAO) in the aetiology of cardiometabolic diseases and chronic kidney disease (CKD), in part via metabolism of ingested food. Using a comparative biomimetic ...
    • Lipidomics reveals seasonal shifts in a large-bodied hibernator, the brown bear 

      Giroud, Sylvain; Chery, Isabelle; Bertile, Fabrice; Bertrand-Michel, Justine; Tascher, Georg; Gauquelin-Koch, Guillemette; Arnemo, Jon Martin; Swenson, Jon; Singh, Navinder; Lefai, Etienne; Evans, Alina L.; Simon, Chantal; Blanc, Stéphane (Peer reviewed; Journal article, 2019)
    • Seasonal changes in eicosanoid metabolism in the brown bear 

      Giroud, Sylvain; Evans, Alina L.; Chery, Isabelle; Bertile, Fabrice; Tascher, Georg; Bertrand-Michel, Justine; Gauquelin-Koch, Guillemette; Arnemo, Jon Martin; Swenson, Jon; Lefai, Etienne; Blanc, Stéphane; Simon, Chantal (Peer reviewed; Journal article, 2018)