Browsing Brage INN by Author "Stensløkken, Kåre-Olav"

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Extreme anoxia tolerance in crucian carp and goldfish through neofunctionalization of duplicated genes creating a new ethanol- producing pyruvate decarboxylase pathway

Fagernes, Cathrine Elisabeth; Stensløkken, Kåre-Olav; Kjendseth, Åsmund Røhr; Berenbrink, Michael; Ellefsen, Stian; Nilsson, Göran Erik (Journal article; Peer reviewed, 2017)

Without oxygen, most vertebrates die within minutes as they cannot meet cellular energy demands with anaerobic metabolism. However, fish of the genus Carassius (crucian carp and goldfish) have evolved a specialized ...
Life without Oxygen: Gene Regulatory Responses of the Crucian Carp (Carassius carassius) Heart Subjected to Chronic Anoxia

Stensløkken, Kåre-Olav; Ellefsen, Stian; Vasieva, Olga; Fang, Yongxiang; Farrell, Anthony P.; Olohan, Lisa; Vaage, Jarle; Nilsson, Göran E.; Cossins, Andrew R. (Journal article; Peer reviewed, 2014)

Crucian carp are unusual among vertebrates in surviving extended periods in the complete absence of molecular oxygen. During this time cardiac output is maintained though these mechanisms are not well understood. Using a ...