• Cerebral Iron Deposition in Neurodegeneration 

      Dusek, Petr; Hofer, Tim; Alexander, Jan; Roos, Per M.; Aaseth, Jan Olav (Peer reviewed; Journal article, 2022)
      Disruption of cerebral iron regulation appears to have a role in aging and in the pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron accumulation include reactive oxygen species ...
    • Iron chelation in the treatment of neurodegenerative diseases 

      Dusek, Petr; Schneider, Susanne A.; Aaseth, Jan (Journal article; Peer reviewed, 2016)
      Disturbance of cerebral iron regulation is almost universal in neurodegenerative disorders. There is a growing body of evidence that increased iron deposits may contribute to degenerative changes. Thus, the effect of iron ...
    • Prevention of progression in Parkinson’s disease 

      Aaseth, Jan; Dusek, Petr; Roos, Per M. (Peer reviewed; Journal article, 2018)
      Environmental influences affecting genetically susceptible individuals seem to contribute significantly to the development of Parkinson’s disease (PD). Xenobiotic exposure including transitional metal deposition into ...
    • Treatment strategies in Alzheimer’s disease: a review with focus on selenium supplementation 

      Aaseth, Jan; Alexander, Jan; Bjørklund, Geir; Hestad, Knut; Dusek, Petr; Roos, Per M.; Alehagen, Urban (Journal article; Peer reviewed, 2016)
      Alzheimer’s disease (AD) is a neurodegenerative disorder presenting one of the biggest healthcare challenges in developed countries. No effective treatment exists. In recent years the main focus of AD research has been on ...