• Metabolic reprogramming involving glycolysis in the hibernating brown bear skeletal muscle 

      Chazarin, Blandine; Storey, Kenneth B.; Ziemianin, Anna; Chanon, Stéphanie; Plumel, M.; Chery, Isabelle; Durand, Christine; Evans, Alina L.; Arnemo, Jon Martin; Zedrosser, Andreas; Swenson, Jon; Gauquelin-Koch, Guillemette; Simon, Chantal; Blanche, Stephane; Lefai, Etienne; Bertile, Fabrice (Peer reviewed; Journal article, 2019)
    • Proteolysis inhibition by hibernating bear serum leads to increased protein content in human muscle cells 

      Chanon, Stéphanie; Chazarin, Blandine; Toubhans, Benoit; Durand, Christine; Chery, Isabelle; Robert, Maud; Vieille-Marchiset, Aurélie; Swenson, Jon; Zedrosser, Andreas; Evans, Alina L.; Brunberg, Sven; Arnemo, Jon Martin; Gauquelin-Koch, Guillemette; Storey, Kenneth B.; Simon, Chantal; Blanc, Stéphane; Bertile, Fabrice; Lefai, Etienne (Journal article; Peer reviewed, 2018)
      Muscle atrophy is one of the main characteristics of human ageing and physical inactivity, with resulting adverse health outcomes. To date, there are still no efcient therapeutic strategies for its prevention and/or ...
    • Specific shifts in the endocannabinoid system in hibernating brown bears 

      Boyer, Christian; Cussonneau, Laura; Brun, Charlotte; Deval, Christiane; Pais de Barros, Jean-Paul; Chanon, Stéphanie; Bernoud-Hubac, Nathalie; Daira, Patricia; Evans, Alina L.; Arnemo, Jon Martin; Swenson, Jon; Gauquelin-Koch, Guillemette; Simon, Chantal; Blanc, Stéphane; Combaret, Lydie; Bertile, Fabrice; Lefai, Etienne (Peer reviewed; Journal article, 2020)
      In small hibernators, global downregulation of the endocannabinoid system (ECS), which is involved in modulating neuronal signaling, feeding behavior, energy metabolism, and circannual rhythms, has been reported to possibly ...