• Concurrent BMP signalling maintenance and TGF-β signalling inhibition is a hallmark of natural resistance to muscle atrophy in the hibernating bear 

      Cussonneau, Laura; Boyer, Christian; Brun, Charlotte; Deval, Christiane; Loizon, Emmanuelle; Meugnier, Emmanuelle; Gueret, Elise; Dubois, Emeric; Taillandier, Daniel; Polge, Cecile; Bechet, Daniel; Gauquelin-Koch, Guillemette; Evans, Alina; Arnemo, Jon Martin; Swenson, Jon; Blanc, Stéphane; Simon, Chantal; Lefai, Etienne; Bertile, Fabrice; Combaret, Lydie (Peer reviewed; Journal article, 2021)
      Abstract: Muscle atrophy arises from a multiplicity of physio-pathological situations and has very detrimental consequences for the whole body. Although knowledge of muscle atrophy mechanisms keeps growing, there is still ...
    • Determinants of heart rate in Svalbard reindeer reveal mechanisms of seasonal energy management 

      Trondrud, Liv Monica; Pigeon, Gabriel; Albon, Steve; Arnold, Walter; Evans, Alina; Irvine, R. Justin; Król, Elżbieta; Ropstad, Erik; Stien, Audun; Veiberg, Vebjørn; Speakman, John R.; Loe, Leif Egil (Peer reviewed; Journal article, 2021)
      Seasonal energetic challenges may constrain an animal's ability to respond to changing individual and environmental conditions. Here, we investigated variation in heart rate, a well-established proxy for metabolic rate, ...
    • Evaluation of Medetomidine-Ketamine for Immobilization of Feral Horses in Romania 

      Roşu, Ovidiu; Melega, Iulia; Evans, Alina; Arnemo, Jon M.; Kûker, Susanne (Peer reviewed; Journal article, 2021)
      Feral horses are immobilized for a variety of reasons including population control via contraceptives. Although opioid combinations have been successfully used for immobilization of feral horses, there is a need for ...
    • Evaluation of three medetomidine-based anesthetic protocols for chemical immobilization of wild boars (Sus scrofa) 

      Morelli, Jacopo; Rossi, Sophie; Fuchs, Boris; Barros, Daniela Sá Braz; Richard, Emmanuelle; Kûker, Susanne; Arnemo, Jon Martin; Evans, Alina (Peer reviewed; Journal article, 2021)
      Three medetomidine-based drug protocols were compared by evaluating time courses, reliability and physiological effects in wild boars. A total of 21 cage-trapped wild boars (Sus scrofa) were immobilized using one of the ...
    • Fat storage influences fasting endurance more than body size in an ungulate 

      Trondrud, Liv Monica; Pigeon, Gabriel; Król, Elżbieta; Albon, Steve; Evans, Alina; Arnold, Walter; Hambly, Catherine; Irvine, R. Justin; Ropstad, Erik; Stien, Audun; Veiberg, Vebjørn; Speakman, John R.; Loe, Leif Egil (Peer reviewed; Journal article, 2021)
      The fasting endurance hypothesis (FEH) predicts strong selection for large body size in mammals living in environments where food supply is interrupted over prolonged periods of time. The Arctic is a highly seasonal and ...
    • Hibernating brown bears are protected against atherogenic dyslipidemia 

      Giroud, Sylvain; Chery, Isabelle; Arrivé, Mathilde; Prost, Michel; Zumsteg, Julie; Heintz, Dimitri; Evans, Alina; Gauquelin-Koch, Guillemette; Arnemo, Jon Martin; Swenson, Jon E.; Lefai, Etienne; Bertile, Fabrice; Simon, Chantal; Blanc, Stéphane (Peer reviewed; Journal article, 2021)
      To investigate mechanisms by which hibernators avoid atherogenic hyperlipidemia during hibernation, we assessed lipoprotein and cholesterol metabolisms of free-ranging Scandinavian brown bears (Ursus arctos). In winter- ...
    • High concentrations of lead (Pb) in blood and milk of free-ranging brown bears (Ursus arctos) in Scandinavia 

      Fuchs, Boris; Thiel, Alexandra; Zedrosser, Andreas; Brown, Ludovick; Hydeskov, Helle Bernstorf; Rodushkin, Ilia; Evans, Alina; Boesen, Amanda Høyer; Græsli, Anne Randi; Kindberg, Jonas; Arnemo, Jon Martin (Peer reviewed; Journal article, 2021)
      Exposure to lead (Pb) is a global health problem for both humans and wildlife. Despite a dramatic decline in human Pb exposure following restrictions of leaded gasoline and industry and thereby an overall reduction of Pb ...
    • High concentrations of lead (Pb) in blood and milk of free-ranging brown bears (Ursus arctos) in Scandinavia 

      Fuchs, Boris; Thiel, Alexandra; Zedrosser, Andreas; Brown, Ludovick; Hydeskov, Helle Bernstorf; Rodushkin, Ilia; Evans, Alina; Boesen, Amanda Høyer; Græsli, Anne Randi; Kindberg, Jonas; Arnemo, Jon Martin (Peer reviewed; Journal article, 2021)
      Exposure to lead (Pb) is a global health problem for both humans and wildlife. Despite a dramatic decline in human Pb exposure following restrictions of leaded gasoline and industry and thereby an overall reduction of Pb ...
    • Seasonality in Biological Rhythms in Scandinavian brown Bears 

      Thiel, Alexandra; Giroud, Sylvain; Hertel, Anne Gabriela; Friebe, Andrea; Devineau, Olivier; Fuchs, Boris; Blanc, Stephane; Støen, Ole-Gunnar; Laske, Timothy G.; Arnemo, Jon Martin; Evans, Alina (Peer reviewed; Journal article, 2022)
      Biological rhythms, such as rhythms in activity and body temperature, are usually highly synchronized and entrained by environmental conditions, such as photoperiod. However, how the expression of these rhythms changes ...