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Browsing Brage INN by Author "Farup, Per Grønaas"

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    • APOE – a genetic marker of comorbidity in subjects with morbid obesity 

      Farup, Per Grønaas; Rootwelt, Helge; Hestad, Knut (Peer reviewed; Journal article, 2020)
      Background: In population-based studies, the genetic variability of the APOE E alleles have been associated with health outcomes. Health problems are common in subjects with obesity. This study explored associations between ...
    • Cognitive Functions and Depression in Patients with Irritable Bowel Syndrome 

      Farup, Per Grønaas; Hestad, Knut (Journal article; Peer reviewed, 2015-04-15)
      Background. Irritable bowel syndrome (IBS) is associated with depression and depression with impaired cognitive functions. The primary aim was to study associations between depression and cognitive functions in patients ...
    • Faecal short-chain fatty acids - a diagnostic biomarker for irritable bowel syndrome? 

      Farup, Per Grønaas; Rudi, Knut; Hestad, Knut (Journal article; Peer reviewed, 2016)
      Background The diagnosis of irritable bowel syndrome (IBS) relies on symptom-based criteria. A valid and reliable biomarker that could confirm the diagnosis is desirable. This study evaluated the properties of faecal ...
    • Functional Bowel Disorders Are Associated with a Central Immune Activation 

      Farup, Per Grønaas; Ueland, Thor; Rudi, Knut; Lydersen, Stian; Hestad, Knut (Peer reviewed; Journal article, 2017)
      Background. Subjects with depression and unexplained neurological symptoms have a high prevalence of gastrointestinal comorbidity probably related to the brain-gut communication. This study explored associations between ...
    • Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis 

      Hestad, Knut; Engedal, Knut; Aukrust, Pål; Farup, Per Grønaas; Mollnes, Tom Eirik; Ueland, Thor; Whist, Jon Elling (Journal article; Peer reviewed, 2016)
      Introduction: Several reports indicate that inflammation may play a role in depression and demonstrate enhanced systemic levels of inflammatory mediators. We hypothesized that 44 patients with a diagnosis of depression ...
    • The effect of ApoE e4 on blood pressure in patients with and without depression 

      Hestad, Knut; Engedal, Knut; Whist, Jon Elling; Farup, Per Grønaas (Journal article; Peer reviewed, 2016)
      Introduction: Depression is considered an independent risk factor for hypertension, particularly for people with recurrent episodes or a long history of depression. Another risk factor for cardiovascular disease is the ...
    • The Relationships among Tryptophan, Kynurenine, Indoleamine 2,3-Dioxygenase, Depression, and Neuropsychological Performance 

      Hestad, Knut; Engedal, Knut; Whist, Jon Elling; Farup, Per Grønaas (Peer reviewed; Journal article, 2017)
      It has been suggested that the metabolic enzyme indoleamine 2,3-dioxygenase (IDO) is a biological mediator of inflammation related to the psychopathology of depression, with a Kynurenine (KYN) increase in the Tryptophan ...

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