Browsing Brage INN by Author "Opstad, Trine Baur"
Now showing items 1-6 of 6
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Changes in circulating sirtuin 1 after bariatric surgery
Opstad, Trine Baur; Farup, Per Grønaas; Rootwelt, Helge; Aaseth, Jan (Peer reviewed; Journal article, 2022)Background and aims: Obesity is associated with chronic inflammation and oxidative stress. Weight loss after bariatric surgery improves the inflammatory state and risk of cardiovascular disease. Improvement in metabolic ... -
Effects of an Intervention with Selenium and Coenzyme Q<inf>10</inf> on Five Selected Age-Related Biomarkers in Elderly Swedes Low in Selenium: Results That Point to an Anti-Ageing Effect—A Sub-Analysis of a Previous Prospective Double-Blind Placebo-Controlled Randomised Clinical Trial
Alehagen, Urban; Alexander, Jan; Aaseth, Jan; Larsson, Anders; Svensson, Erland; Opstad, Trine Baur (Peer reviewed; Journal article, 2023)Background: Ageing is associated with cardiovascular disease (CVD). As no single biomarker reflects the full ageing process, we aimed to investigate five CVD- and age-related markers and the effects of selenium and coenzyme ... -
Increased SIRT1 Concentration Following Four Years of Selenium and Q<inf>10</inf> Intervention Associated with Reduced Cardiovascular Mortality at 10-Year Follow-Up—Sub-Study of a Previous Prospective Double-Blind Placebo-Controlled Randomized Clinical Trial
Opstad, Trine Baur; Alexander, Jan; Aaseth, Jan; Larsson, Anders; Seljeflot, Ingebjørg; Alehagen, Urban (Peer reviewed; Journal article, 2023)Background: Selenium and coenzyme Q10 (SeQ10) possess antioxidant and anti-inflammatory properties, potentially mediated via Sirtuin1 (SIRT1). We aimed to investigate the influence of a SeQ10 intervention on SIRT1 ... -
Selenium and Coenzyme Q<inf>10</inf> Intervention Prevents Telomere Attrition, with Association to Reduced Cardiovascular Mortality-Sub-Study of a Randomized Clinical Trial
Opstad, Trine Baur; Alexander, Jan; Aaseth, Jan; Larsson, Anders; Seljeflot, Ingebjørg; Alehagen, Urban (Peer reviewed; Journal article, 2022)Short telomeres have been associated with ageing and cardiovascular disease. The influence on leukocyte telomere length (LTL) of long-term intervention with combined selenium and coenzyme Q10 is unknown. Our aim was to ... -
Supplementation with selenium and coenzyme Q<inf>10</inf> in an elderly Swedish population low in selenium — positive effects on thyroid hormones, cardiovascular mortality, and quality of life
Alehagen, Urban; Alexander, Jan; Aaseth, Jan; Larsson, Anders; Opstad, Trine Baur (Peer reviewed; Journal article, 2024)Background Selenium-dependent deiodinases play a central role in thyroid hormone regulation and metabolism. In many European countries, insufficient selenium intake may consequently lead to adverse effects on thyroid ... -
Vitamin K and Calcium Chelation in Vascular Health
Aaseth, Jan; Alehagen, Urban; Opstad, Trine Baur; Alexander, Jan (Peer reviewed; Journal article, 2023)The observation that the extent of artery calcification correlates with the degree of atherosclerosis was the background for the alternative treatment of cardiovascular disease with chelator ethylenediamine tetraacetate ...