Browsing Brage INN by Journals "Scientific Reports"
Now showing items 1-20 of 26
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An intragenic mutagenesis strategy in Physcomitrella patens to preserve intron splicing.
(Journal article; Peer reviewed, 2017)Gene targeting is a powerful reverse genetics technique for site-specific genome modification. Intrinsic homologous recombination in the moss Physcomitrella patens permits highly effective gene targeting, a characteristic ... -
Associations of the serotonin transporter gene polymorphism, 5-HTTLPR, and adverse life events with late life depression in the elderly Lithuanian population
(Peer reviewed; Journal article, 2023)Late-life depression (LLD) is a multifactorial disorder, with susceptibility and vulnerability potentially influenced by gene-environment interaction. The aim of this study was to investigate whether the 5-HTTLPR polymorphism ... -
Brown bear attacks on humans: a worldwide perspective
(Peer reviewed; Journal article, 2019)The increasing trend of large carnivore attacks on humans not only raises human safety concerns but may also undermine large carnivore conservation efforts. Although rare, attacks by brown bears Ursus arctos are also on ... -
Cardiac adaptation in hibernating, free-ranging Scandinavian Brown Bears (Ursus arctos)
(Peer reviewed; Journal article, 2020)During six months of annual hibernation, the brown bear undergoes unique physiological changes to adapt to decreased metabolic rate. We compared cardiac structural and functional measures of hibernating and active bears ... -
Culture dependent and independent analyses suggest a low level of sharing of endospore-forming species between mothers and their children
(Peer reviewed; Journal article, 2020)Spore forming bacteria comprise a large part of the human gut microbiota. However, study of the endospores in gut microbiota is limited due to difficulties of culturing and numerous unknown germination factors. In this ... -
Defining animal welfare standards in hunting: body mass determines thresholds for incapacitation time and flight distance
(Peer reviewed; Journal article, 2018) -
Demography of a Eurasian lynx (Lynx lynx) population within a strictly protected area in Central Europe
(Peer reviewed; Journal article, 2021)Large carnivores promote crucial ecosystem processes but are increasingly threatened by human persecution and habitat destruction. Successful conservation of this guild requires information on long-term population dynamics ... -
The effects of gas flaring as moderated by government quality in leading natural gas flaring economies
(Peer reviewed; Journal article, 2023)This study seeks to address pertinent economic and environmental issues associated with natural gas flaring, especially for the world's leading natural gas flaring economies (i.e. Russia, Iraq, Iran, the United States, ... -
Explicit integration of dispersal-related metrics improves predictions of SDM in predatory arthropods
(Peer reviewed; Journal article, 2020-10-07)Fishing spiders (Dolomedes spp.) make an interesting model to predict the impact of global changes because they are generalist, opportunistic predators, whose distribution is driven mostly by abiotic factors. Yet, the two ... -
Extreme anoxia tolerance in crucian carp and goldfish through neofunctionalization of duplicated genes creating a new ethanol- producing pyruvate decarboxylase pathway
(Journal article; Peer reviewed, 2017)Without oxygen, most vertebrates die within minutes as they cannot meet cellular energy demands with anaerobic metabolism. However, fish of the genus Carassius (crucian carp and goldfish) have evolved a specialized ... -
Hibernating brown bears are protected against atherogenic dyslipidemia
(Peer reviewed; Journal article, 2021)To investigate mechanisms by which hibernators avoid atherogenic hyperlipidemia during hibernation, we assessed lipoprotein and cholesterol metabolisms of free-ranging Scandinavian brown bears (Ursus arctos). In winter- ... -
Impact of a recolonizing, cross‑border carnivore population on ungulate harvest in Scandinavia
(Peer reviewed; Journal article, 2020)Predation from large carnivores and human harvest are the two main mortality factors afecting the dynamics of many ungulate populations. We examined long-term moose (Alces alces) harvest data from two countries that share ... -
Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears
(Peer reviewed; Journal article, 2020)Experimental studies suggest involvement of trimethylamine N-oxide (TMAO) in the aetiology of cardiometabolic diseases and chronic kidney disease (CKD), in part via metabolism of ingested food. Using a comparative biomimetic ... -
Mapping patterns of abiotic and biotic stress resilience uncovers conservation gaps and breeding potential of Vigna wild relatives
(Peer reviewed; Journal article, 2020)This study provides insights in patterns of distribution of abiotic and biotic stress resilience across Vigna gene pools to enhance the use and conservation of these genetic resources for legume breeding. Vigna is a ... -
A mixed-methods exploration of virtual reality as a tool to promote green exercise
(Peer reviewed; Journal article, 2022)The salutogenic effects of green exercise are widely recognised, yet many individuals do not engage in this health-related behaviour. Using a convergent mixed methods approach, this study explored the impact of Virtual ... -
On the interplay between hypothermia and reproduction in a high arctic ungulate
(Peer reviewed; Journal article, 2020)For free-ranging animals living in seasonal environments, hypometabolism (lowered metabolic rate) and hypothermia (lowered body temperature) can be effective physiological strategies to conserve energy when forage resources ... -
Proteolysis inhibition by hibernating bear serum leads to increased protein content in human muscle cells
(Journal article; Peer reviewed, 2018)Muscle atrophy is one of the main characteristics of human ageing and physical inactivity, with resulting adverse health outcomes. To date, there are still no efcient therapeutic strategies for its prevention and/or ... -
Rapid identification of pathogens, antibiotic resistance genes and plasmids in blood cultures by nanopore sequencing
(Peer reviewed; Journal article, 2020)Bloodstream infections (BSI) and sepsis are major causes of morbidity and mortality worldwide. Blood culture-based diagnostics usually requires 1–2 days for identification of bacterial agent and an additional 2–3 days for ... -
Retinal venular vessel diameters are smaller during ten days of bed rest
(Peer reviewed; Journal article, 2023)Older individuals experience cardiovascular dysfunction during extended bedridden hospital or care home stays. Bed rest is also used as a model to simulate accelerated vascular deconditioning occurring during spaceflight. ... -
Smartphone app reveals that lynx avoid human recreationists on local scale, but not home range scale
(Peer reviewed; Journal article, 2022)Outdoor recreation is increasing and affects habitat use and selection by wildlife. These effects are challenging to study, especially for elusive species with large spatial requirements, as it is hard to obtain reliable ...