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dc.contributor.authorLog, Tomas
dc.contributor.authorSkurtveit, Svetlana
dc.contributor.authorSelmer, Randi
dc.contributor.authorTverdal, Åge
dc.contributor.authorFuru, Kari
dc.contributor.authorHartz, Ingeborg
dc.date.accessioned2013-12-04T11:32:50Z
dc.date.available2014-02-01T00:01:45Z
dc.date.issued2013
dc.identifier.citationLog, T., Skurtveit, S., Selmer, R.M., Tverdal, A., Furu, K. & Hartz, I. (2013). The association between prescribed opioid use for mothers and children: A record-linkage study. European Journal of Clinical Pharmacology 69(1), 111–118.no_NO
dc.identifier.urihttp://hdl.handle.net/11250/134640
dc.descriptionDette er forfatters versjon av artikkelen. Forlagets publiserte versjon finnes på http://link.springer.comno_NO
dc.description.abstractRepeated use of prescribed opioids may lead to serious side effects, and it is important to examine risk factors for repeated use. The aim of this study was to investigate the association between maternal use of prescribed opioids and the use of prescribed opioids by their offspring. Data were drawn from two nationwide registers linked by the unique person identity numbers: the Norwegian Population and Housing Census in 2001 and the Norwegian Prescription Database (2004-2009). The study population consisted of 97,574 adolescents aged 15-16 years in 2001 and their mothers. Repeated use of opioids was defined as filling 4+ and 15+ prescriptions during 2004-2009 by the offspring and mothers, respectively. Non-steroidal anti-inflammatory drugs (NSAIDs) are not potentially addictive, and were used as a reference analgesic drug group. The proportion of repeated users were higher among individuals whose mothers were registered with repeated use of opioids (8.4 %) compared to those with mothers without repeated use (2.4 %). Odds ratio was 3.1 (95% CI 2.7-3.6) when adjusted for mothers socioeconomic characteristics and the gender of the offspring. Low maternal socio-economic status increased the risk of repeated opioid use among their offspring. Maternal repeated use of NSAIDs increased the likelihood of repeated use of NSAIDs among offspring OR 1.8 (95% CI 1.7 – 2.0).no_NO
dc.language.isoengno_NO
dc.publisherSpringerno_NO
dc.relation.urihttp://link.springer.com
dc.subjectopioidsno_NO
dc.subjectmother-child relationsno_NO
dc.subjectpharmacoepidemiologyno_NO
dc.subjectopioiderno_NO
dc.subjectmor-barn-relasjonerno_NO
dc.subjectfarmakoepidemiologino_NO
dc.titleAssociation of prescribed opioid use between mother and child – a record-linkage studyno_NO
dc.typePeer reviewedno_NO
dc.typeJournal article
dc.subject.nsiVDP::Medical disciplines: 700::Health sciences: 800no_NO
dc.source.pagenumber111-118no_NO
dc.source.volume69no_NO
dc.source.journalEuropean Journal of Clinical Pharmacologyno_NO
dc.source.issue1no_NO
dc.identifier.doihttp://dx.doi.org/10.1007/s00228-012-1312-8


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