Blar i Brage INN på forfatter "Fröbert, Ole"
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Adipose-derived stem cells from the brown bear (Ursus arctos) spontaneously undergo chondrogenic and osteogenic differentiation
Fink, Trine; Rasmussen, Jeppe G.; Emmersen, Jeppe; Fahlman, Åsa; Brunberg, Sven; Josefsson, Johan; Arnemo, Jon Martin; Zachar, Vladimir; Swenson, Jon E.; Fröbert, Ole (Journal article; Peer reviewed, 2011)In the den, hibernating brown bears do not develop tissue atrophy or organ damage, despite almost no physical activity. Mesenchymal stem cells could play an important role in tissue repair and regeneration in brown bears. ... -
Adipose-derived stem cells from the brown bear (Ursus arctos) spontaneously undergo chondrogenic and osteogenic differentiation in vitro
Fink, Trine; Rasmussen, Jeppe; Emmersen, Jeppe; Pilgaard, Linda; Fahlman, Åsa; Brunberg, Sven; Josefsson, Johan; Arnemo, Jon Martin; Zachar, Vladimir; Swenson, Jon; Fröbert, Ole (Peer reviewed; Journal article, 2011) -
Body Temperature during Hibernation Is Highly Correlated with a Decrease in Circulating Innate Immune Cells in the Brown Bear (Ursus arctos): A Common Feature among Hibernators?
Sahdo, Berolla; Evans, Alina L.; Arnemo, Jon Martin; Fröbert, Ole; Särndahl, Eva; Blanc, Stéphane (Journal article; Peer reviewed, 2013)Background: Hibernation involves periods of severely depressed metabolism (torpor) and decreases in body temperature (Tb). Small arctic mammals (<5kg), in which Tb generally drop drastically, display leukopenia during ... -
Capture, Anesthesia, and Disturbance of Free-Ranging Brown Bears (Ursus arctos) during Hibernation
Evans, Alina L.; Sahlén, Veronica; Støen, Ole-Gunnar; Fahlman, Åsa; Brunberg, Sven; Madslien, Knut; Fröbert, Ole; Swenson, Jon E.; Arnemo, Jon Martin (Journal article; Peer reviewed, 2012)We conducted thirteen immobilizations of previously collared hibernating two- to four-year-old brown bears (Ursus arctos) weighing 21–66 kg in central Sweden in winter 2010 and 2011 for comparative physiology research. ... -
Capture, Anesthesia, and Disturbance of Free-Ranging Brown Bears (Ursus arctos) during Hibernation
Evans, Alina; Sahlén, Veronica; Støen, Ole-Gunnar; Fahlman, Åsa; Brunberg, Sven; Madslien, Knut; Fröbert, Ole; Swenson, Jon; Arnemo, Jon Martin (Peer reviewed; Journal article, 2012)We conducted thirteen immobilizations of previously collared hibernating two- to four-year-old brown bears (Ursus arctos) weighing 21–66 kg in central Sweden in winter 2010 and 2011 for comparative physiology research. ... -
Cardiac adaptation in hibernating, free-ranging Scandinavian Brown Bears (Ursus arctos)
Jørgensen, Peter Godsk; Evans, Alina; Kindberg, Jonas; Olsen, Lisbeth Høier; Galatius, Søren; Fröbert, Ole (Peer reviewed; Journal article, 2020)During six months of annual hibernation, the brown bear undergoes unique physiological changes to adapt to decreased metabolic rate. We compared cardiac structural and functional measures of hibernating and active bears ... -
Development and utilization of implantable cardiac monitors in free-ranging American black and Eurasian brown bears: System evolution and lessons learned
Laske, Timothy G.; Evans, Alina; Arnemo, Jon Martin; Iles, Tinen L.; Ditmer, Mark A.; Fröbert, Ole; Garshelis, David L.; Iaizzo, Paul A. (Peer reviewed; Journal article, 2018) -
Hydrogen sulfide and nitric oxide metabolites in the blood of free-ranging brown bears and their potential roles in hibernation
Revsbech, Inge G; Shen, Xinggui; Chakravarti, Ritu; Jensen, Frank B.; Thiel, Bonnie; Evans, Alina L.; Kindberg, Jonas; Fröbert, Ole; Stuehr, Dennis J.; Kevil, Christopher G.; Fago, Angela (Journal article; Peer reviewed, 2014)During winter hibernation, brown bears (Ursus arctos) lie in dens for half a year without eating while their basal metabolism is largely suppressed. To understand the underlying mechanisms of metabolic depression in ... -
Physiological evidence for a human-induced landscape of fear in brown bears (Ursus arctos)
Støen, Ole Gunnar; Ordiz, Andres; Evans, Alina; Laske, Timothy G.; Kindberg, Jonas; Fröbert, Ole; Swenson, Jon E.; Arnemo, Jon Martin (Journal article; Peer reviewed, 2015)Human persecution is a major cause of mortality for large carnivores. Consequently, large carnivores avoid humans, but may use human-dominated landscapes by being nocturnal and elusive. Behavioral studies indicate that ... -
Physiological reactions to capture in hibernating brown bears
Evans, Alina; Singh, Navinder J.; Fuchs, Boris; Blanc, Stéphane; Friebe, Andrea; Laske, Timothy; Fröbert, Ole; Swenson, Jon; Arnemo, Jon Martin (Peer reviewed; Journal article, 2016) -
Platelet function in brown bear (Ursus arctos) compared to man
Fröbert, Ole; Christensen, Kjeld; Fahlman, Åsa; Brunberg, Sven; Josefsson, Johan; Särndahl, Eva; Swenson, Jon E.; Arnemo, Jon Martin (Journal article; Peer reviewed, 2010)Background: Information on hemostasis and platelet function in brown bear (Ursus arctos) is of importance for understanding the physiological, protective changes during hibernation. Objective: The study objective was to ... -
The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos
Sommer, Felix; Ståhlman, Marcus; Ilkayeva, Olga; Arnemo, Jon Martin; Kindberg, Jonas; Josefsson, Johan; Newgard, Christopher B; Fröbert, Ole; Bäckhed, Fredrik (Journal article; Peer reviewed, 2016)Hibernation is an adaptation that helps many animals to conserve energy during food shortage in winter. Brown bears double their fat depots during summer and use these stored lipids during hibernation. Although bears ...