Browsing Brage INN by Author "Hestad, Knut"
Now showing items 1-20 of 34
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APOE Polymorphism and Endocrine Functions in Subjects with Morbid Obesity Undergoing Bariatric Surgery
Farup, Per Grønaas; Jansen, Aina; Hestad, Knut; Aaseth, Jan; Rootwelt, Helge (Peer reviewed; Journal article, 2022)Background: Obesity is an interplay between genes and the environment, including lifestyle. The genetics of obesity is insufficiently understood. Apolipoprotein E (APOE) genetic polymorphism has been associated with a wide ... -
APOE – a genetic marker of comorbidity in subjects with morbid obesity
Farup, Per Grønaas; Rootwelt, Helge; Hestad, Knut (Peer reviewed; Journal article, 2020)Background: In population-based studies, the genetic variability of the APOE E alleles have been associated with health outcomes. Health problems are common in subjects with obesity. This study explored associations between ... -
Apolipoprotein E (APOE) allelet er av vesentlig betydning for hukommelse og demensutvikling hos de eldste
Hestad, Knut; Strand, Bjørn Heine; Engedal, Knut (Peer reviewed; Journal article, 2023)De mest typiske patologiske forandringene i hjernen ved Alzheimers sykdom er avleiring av beta-amyloid i nevritiske plakk ekstracellulært, samt dannelse av nevrofibrillære floker intracellulært grunnet endring av tau-protein. ... -
The Applicability of the Patient-Specific Functional Scale (PSFS) in Rehabilitation for Patients with Acquired Brain Injury (ABI) – A Cohort Study
Evensen, Janne; Søberg, Helene Lundgaard; Sveen, Unni; Hestad, Knut; Bronken, Berit Arnesveen (Peer reviewed; Journal article, 2020)Aim: The primary aim of this study was to investigate the applicability of the Patient-Specific Functional Scale (PSFS) in patients with acquired brain injury (ABI) admitted to a specialized rehabilitation unit in a regional ... -
Blood Pressure and T-Tau in Spinal Fluid Are Associated With Delayed Recall in Participants With Memory Complaints and Dementia of the Alzheimer’s Type
Hestad, Knut; Horndalsveen, Peter Otto; Engedal, Knut (Peer reviewed; Journal article, 2021)Objective: The aim of the study was to determine if systolic blood pressure (SBP), total-tau (t-tau), and beta-amyloid (Aβ) in the cerebral spinal fluid (CSF) were associated with the results on the Consortium to Establish ... -
Blood pressure in dementia, mild cognitive impairment, and subjective cognitive decline related to time of death
Hestad, Knut; Engedal, Knut; Selbæk, Geir; Strand, Bjørn Heine (Peer reviewed; Journal article, 2021)Objective: It is unknown whether systolic blood pressure (SBP) drop is part of the normal aging process or due to the onset of dementia for some people. SBP drop is referring to the decrease in blood pressure often seen ... -
Blood Pressure in Different Dementia Disorders, Mild Cognitive Impairment, and Subjective Cognitive Decline
Hestad, Knut; Engedal, Knut; Horndalsveen, Peter; Strand, Bjørn Heine (Peer reviewed; Journal article, 2020)The aim of the study was to investigate whether blood pressure (BP) differed among people with different dementia diagnoses, mild cognitive impairment, and subjective cognitive decline and whether BP differences were ... -
Blood pressure trajectories over 35 years and dementia risk: A retrospective study: The HUNT study
Selbæk, Geir; Stuebs, Josephine; Engedal, Knut; Hachinski, Vladimir; Hestad, Knut; Treviño, Cathrine Selnes; Skjellegrind, Håvard; Wedatilake, Yehani; Strand, Bjørn Heine (Peer reviewed; Journal article, 2022-09-15)High blood pressure is a well-established risk factor of dementia. However, the timing of the risk remains controversial. The aim of the present study was to compare trajectories of systolic blood pressure (SBP) over a ... -
Circulating Lipoproteins in Subjects with Morbid Obesity Undergoing Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy
Aaseth, Jan; Rootwelt, Helge; Retterstøl, Kjetil; Hestad, Knut; Farup, Per Grønaas (Peer reviewed; Journal article, 2022)The efficacy of various bariatric procedures on the mitigation of the obese dyslipidemia remains debated, and the impact of these measures on lipoprotein(a) (Lp(a)) levels is unknown. In this study we aimed to compare the ... -
Cognition in Patients With Memory Difficulties and Dementia Relative to APOE e4 Status
Hestad, Knut; Engedal, Knut; Horndalsveen, Peter Otto; Strand, Bjørn Heine (Peer reviewed; Journal article, 2021)The aim of this study was to investigate whether cognitive performance was equally influenced by Apolipoprotein E (APOE, with its three alleles, e2, e3, and e4) in patients with subjective cognitive decline (SCD), mild ... -
Cognitive Functions and Depression in Patients with Irritable Bowel Syndrome
Farup, Per Grønaas; Hestad, Knut (Journal article; Peer reviewed, 2015-04-15)Background. Irritable bowel syndrome (IBS) is associated with depression and depression with impaired cognitive functions. The primary aim was to study associations between depression and cognitive functions in patients ... -
Effect of Age and Level of Education on Neurocognitive Impairment in HIV Positive Zambian Adults
Kabuba, Norma Namasiku Zewelanji; Menon, Anitha; Franklin, Donald R.; Lydersen, Stian; Heaton, Robert K.; Hestad, Knut (Peer reviewed; Journal article, 2018)Objective: Older age and lower education levels are known to be associated with worse neurocognitive (NC) performance in healthy adults, and individuals with HIV infection may experience accelerated brain/cognition aging. ... -
Faecal short-chain fatty acids - a diagnostic biomarker for irritable bowel syndrome?
Farup, Per Grønaas; Rudi, Knut; Hestad, Knut (Journal article; Peer reviewed, 2016)Background The diagnosis of irritable bowel syndrome (IBS) relies on symptom-based criteria. A valid and reliable biomarker that could confirm the diagnosis is desirable. This study evaluated the properties of faecal ... -
Fra ensidighet til gjensidighet: Samhandling om pasienter med langvarige og sammensatte behov
Danbolt, Lars Johan; Hestad, Knut; Kjønsberg, Kari; Kvalvik, Ann-Mari; Hynnekleiv, Torfinn (Journal article; Peer reviewed, 2016)The purpose of the study was to explore health care professionals’ experiences of collaboration across service levels concerning people with long term and complex mental disorders, and these professionals’ reflections on ... -
Functional Bowel Disorders Are Associated with a Central Immune Activation
Farup, Per Grønaas; Ueland, Thor; Rudi, Knut; Lydersen, Stian; Hestad, Knut (Peer reviewed; Journal article, 2017)Background. Subjects with depression and unexplained neurological symptoms have a high prevalence of gastrointestinal comorbidity probably related to the brain-gut communication. This study explored associations between ... -
HIV- and AIDS-associated neurocognitive functioning in Zambia - a perspective based on differences between the genders
Kabuba, Norma Namasiku Zewelanji; Menon, J. A.; Franklin, D.R. jr.; Heaton, R. K.; Hestad, Knut (Journal article; Peer reviewed, 2016)Human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS) are frequently associated with neurocognitive impairment (NCI). However, few studies have examined the interrelationship between ... -
Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls
Hestad, Knut; Weider, Siri; Nilsen, Kristian Bernhard; Indredavik, Marit Sæbø; Sand, Trond (Journal article; Peer reviewed, 2016)Objective: To conduct a blind study of quantitative electroencephalogram-band amplitudes in patients with anorexia nervosa (AN) and healthy controls. Methods: Twenty-one patients with AN and 24 controls were examined with ... -
Individualized goals expressed by patients undergoing stroke rehabilitation: an observational study
Evensen, Janne; Søberg, Helene L.; Sveen, Unni; Hestad, Knut; Moore, Jennifer L.; Bronken, Berit Arnesveen (Peer reviewed; Journal article, 2024)Objectives: To explore the rehabilitation goals measured with the Patient-Specific Functional Scale (PSFS) in patients undergoing acute and subacute stroke rehabilitation. In addition, to assess whether PSFS goals corresponded ... -
The Kynurenine Pathway in Healthy Subjects and Subjects with Obesity, Depression and Chronic Obstructive Pulmonary Disease
Farup, Per Grønaas; Hamarsland, Håvard; Mølmen, Knut Sindre; Ellefsen, Stian; Hestad, Knut (Peer reviewed; Journal article, 2023)Background: Changes in tryptophan metabolism through the kynurenine pathway (KP) are observed in several disorders and coupled with pathophysiological deviations. Methods: This study retrospectively compared the KP in serum ... -
Measurement Properties of the Patient-Specific Functional Scale in Rehabilitation for Patients With Stroke: A Prospective Observational Study
Evensen, Janne; Søberg, Helene L.; Sveen, Unni; Hestad, Knut; Moore, Jennifer L.; Bronken, Berit Arnesveen (Peer reviewed; Journal article, 2023-02-13)Objective This study investigated the validity, reliability, responsiveness, and interpretability of the Patient-Specific Functional Scale (PSFS) in subacute stroke rehabilitation to determine its suitability to measure ...