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dc.contributor.authorTremoen, Nina Hårdnes
dc.contributor.authorvan Son, Maren
dc.contributor.authorAndersen-Ranberg, Ina
dc.contributor.authorGrindflek, Eli
dc.contributor.authorMyromslien, Frøydis Deinboll
dc.contributor.authorGaustad, Ann Helen
dc.contributor.authorVåge, Dag Inge
dc.date.accessioned2020-09-17T12:25:02Z
dc.date.available2020-09-17T12:25:02Z
dc.date.created2020-01-22T12:28:27Z
dc.date.issued2019
dc.identifier.citationActa Veterinaria Scandinavica. 2019, 61.en_US
dc.identifier.issn1751-0147
dc.identifier.urihttps://hdl.handle.net/11250/2678291
dc.description.abstractFinding effective predictors of traits related to boar fertility is essential for increasing the efficiency of artificial insemi‑nation systems in pig breeding. The objective of this study was to find associations between single‑nucleotide poly‑morphisms (SNPs) within candidate genes and fertility in the breeds Landrace and Duroc. Animals with breeding val‑ues for total number of piglets born, were re‑sequenced for exonic regions of 14 candidate genes related to male and female fertility using samples from 16 Landrace boars and 16 Duroc boars (four with high and four with low breeding value of total number of piglets born for each breed for male fertility, and the same for female fertility) to detect genetic variants. Genotyping for the detected SNPs was done in 619 Landrace boars and 513 Duroc boars. Two SNPs in BMPR1 and one SNP in COX-2 were found significantly associated with the total number of piglets born in Landrace. In Duroc, two SNPs in PLCz, one SNP in VWF and one SNP in ZP3 were found significantly associated with total number of piglets born. These SNPs explained between 0.27% and 1.18% of the genetic variance. These effects are too low for being used directly for selection purposes but can be of interest in SNP‑panels used for genomic selection.en_US
dc.language.isoengen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.subjectboaren_US
dc.subjectcandidate genesen_US
dc.subjectfertilityen_US
dc.subjectSNPen_US
dc.titleAssociation between single-nucleotide polymorphisms within candidate genes and fertility in Landrace and Duroc pigsen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.subject.nsiVDP::Teknologi: 500en_US
dc.source.pagenumber5en_US
dc.source.volume61en_US
dc.source.journalActa Veterinaria Scandinavicaen_US
dc.identifier.doi10.1186/s13028-019-0493-x
dc.identifier.cristin1779964
dc.relation.projectNorges forskningsråd: 207568en_US
cristin.unitcode209,2,2,0
cristin.unitnameInstitutt for bioteknologi
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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