dc.contributor.author | Rinaldo, Christine Hanssen | |
dc.contributor.author | Nymo, Ingebjørg Helena | |
dc.contributor.author | Sanchez Romano, Javier | |
dc.contributor.author | Breines, Eva Marie | |
dc.contributor.author | Murguzur, Francisco Javier Ancin | |
dc.contributor.author | Tryland, Morten | |
dc.date.accessioned | 2022-06-21T12:53:26Z | |
dc.date.available | 2022-06-21T12:53:26Z | |
dc.date.created | 2021-12-16T12:40:30Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Pathogens. 2021, 10 (12), 1-12. | en_US |
dc.identifier.issn | 2076-0817 | |
dc.identifier.uri | https://hdl.handle.net/11250/2999857 | |
dc.description.abstract | Hepatitis E virus (HEV) is a common cause of viral hepatitis in humans. In developing countries, HEV-infections seem to be mainly associated with pigs, but other animal species may be involved in viral transmission. Recently, anti-HEV antibodies were detected in Norwegian wild reindeer. Here, we investigated anti-HEV seroprevalence in Norwegian semi-domesticated reindeer, animals in closer contact with humans than their wild counterparts. Blood samples (n = 516) were obtained from eight reindeer herds during the period 2013–2017 and analyzed with a commercial enzyme-linked immunosorbent assay designed for detecting anti-HEV antibodies in livestock. Antibodies were found in all herds and for all sampling seasons. The overall seroprevalence was 15.7% (81/516), with adults showing a slightly higher seroprevalence (18.0%, 46/256) than calves (13.5%, 35/260, p = 0.11). The seroprevalence was not influenced by gender or latitude, and there was no temporal trend (p > 0.15). A positive association between the presence of anti-HEV antibodies and antibodies against alphaherpesvirus and pestivirus, detected in a previous screening, was found (p < 0.05). We conclude that Norwegian semi-domesticated reindeer are exposed to HEV or an antigenically similar virus. Whether the virus is affecting reindeer health or infects humans and poses a threat for human health remains unknown and warrants further investigations. | en_US |
dc.language.iso | eng | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.subject | hepatitis E virus | en_US |
dc.subject | Hepeviridae | en_US |
dc.subject | Rangifer | en_US |
dc.subject | serology | en_US |
dc.subject | zoonosis | en_US |
dc.title | Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.subject.nsi | VDP::Matematikk og Naturvitenskap: 400 | en_US |
dc.source.pagenumber | 1-12 | en_US |
dc.source.volume | 10 | en_US |
dc.source.journal | Pathogens | en_US |
dc.source.issue | 12 | en_US |
dc.identifier.doi | 10.3390/pathogens10121542 | |
dc.identifier.cristin | 1969412 | |
dc.source.articlenumber | 1542 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |