dc.contributor.author | Haugen, Ingvild | |
dc.contributor.author | Stubberud, Jan Egil | |
dc.contributor.author | Haug, Elisabeth | |
dc.contributor.author | McGurk, Susan R. | |
dc.contributor.author | Hovik, Kjell Tore | |
dc.contributor.author | Ueland, Torill | |
dc.contributor.author | Øie, Merete Glenne | |
dc.date.accessioned | 2022-12-07T08:26:26Z | |
dc.date.available | 2022-12-07T08:26:26Z | |
dc.date.created | 2022-08-12T10:15:50Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | BMC Psychiatry. 2022, 22 (1), . | en_US |
dc.identifier.issn | 1471-244X | |
dc.identifier.uri | https://hdl.handle.net/11250/3036247 | |
dc.description.abstract | Background Executive functioning is essential to daily life and severely impaired in schizophrenia and psychosis risk syndromes. Goal Management Training (GMT) is a theoretically founded, empirically supported, metacognitive strategy training program designed to improve executive functioning. Methods A randomized controlled parallel group trial compared GMT with treatment as usual among 81 participants (GMT, n = 39 versus Wait List Controls, n = 42) recruited from an early intervention for psychosis setting. Computer generated random allocation was performed by someone independent from the study team and raters post-intervention were unaware of allocation. The primary objective was to assess the impact of GMT administered in small groups for 5 weeks on executive functioning. The secondary objective was to explore the potential of the intervention in influencing daily life functioning and clinical symptoms. Results GMT improved self-reported executive functioning, measured with the Behavior Rating Inventory of Executive Function – Adult version (BRIEF-A), significantly more than treatment as usual. A linear mixed model for repeated measures, including all partial data according to the principle of intention to treat, showed a significant group x time interaction effect assessed immediately after intervention (post-test) and 6 months after intervention (follow-up), F = 8.40, p .005, r .37. Improvement occurred in both groups in objective executive functioning as measured by neuropsychological tests, functional capacity, daily life functioning and symptoms of psychosis rated by clinicians. Self-reported clinical symptoms measured with the Symptoms Check List (SCL-10) improved significantly more after GMT than after treatment as usual, F = 5.78, p .019, r .29. Two participants withdrew due to strenuous testing and one due to adverse effects. Conclusions GMT had clinically reliable and lasting effects on subjective executive function. The intervention is a valuable addition to available treatment with considerable gains at low cost. Trial registration Registered at clinicaltrials.gov NCT03048695 09/02/2017. | en_US |
dc.language.iso | eng | en_US |
dc.relation.uri | https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-022-04197-3 | |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.subject | Early intervention | en_US |
dc.subject | Psychosis | en_US |
dc.subject | Executive function | en_US |
dc.subject | Cognitive remediation | en_US |
dc.subject | Cognitive impairment | en_US |
dc.subject | Real world function | en_US |
dc.title | A randomized controlled trial of Goal Management Training for executive functioning in schizophrenia spectrum disorders or psychosis risk syndromes | en_US |
dc.title.alternative | A randomized controlled trial of Goal Management Training for executive functioning in schizophrenia spectrum disorders or psychosis risk syndromes | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.subject.nsi | VDP::Medisinske Fag: 700 | en_US |
dc.source.pagenumber | 17 | en_US |
dc.source.volume | 22 | en_US |
dc.source.journal | BMC Psychiatry | en_US |
dc.source.issue | 1 | en_US |
dc.identifier.doi | 10.1186/s12888-022-04197-3 | |
dc.identifier.cristin | 2042608 | |
dc.relation.project | Universitetet i Oslo: 353139 | en_US |
dc.relation.project | Helse Sør-Øst RHF: 2017012 | en_US |
dc.relation.project | Sykehuset Innlandet HF: 150602 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |